Bridget Owusu
- Country of Origin: Ghana
- Home University: University of Ghana
- Host University & Country: Colorado State University - USA
- PhD Title: Examining the Functional Contributions of the Histone Chaperone Spn1 Structure to Yeast Lifespan Extension
- Year of Completion: 2026
PhD Overview
My research investigates the structural and functional contributions of the histone chaperone Spn1 in regulating yeast lifespan extension, a novel approach to understanding chromatin dynamics in aging. Unlike traditional studies that focus solely on histone modifications, my work explores how specific structural domains of Spn1 influence transcriptional regulation and genome stability over time. By dissecting these mechanisms, this study provides new insights into the interplay between chromatin remodeling and cellular longevity, potentially revealing conserved pathways relevant to aging in higher eukaryotes.
Sustainability Goals
- Good Health and Well-being
- Industry, Innovation and Infrastructure
- Life on Land
About Me
As a Black woman, mother, and scholar at a PWI, I navigate multiple marginalized identities that could have held me back, yet resilience and intelligence define my journey. I have won multiple awards that speak to my depth of knowledge and expertise, including the prestigious Schlumberger Fellowship. My research focuses on how cells control aging by studying a special protein called Spn1, which helps organize DNA. By understanding how Spn1 affects gene activity and cell health, I hope to uncover clues about why some cells live longer than others, which could have important lessons for human aging and disease.